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relapsing polychondritis
Relapsing polychondritis, also known as atrophic polychondritis,〔 systemic chondromalacia) chronic atrophic polychondritis, Meyenburg-Altherr-Uehlinger syndrome, and generalized chondromalacia, is a multi-systemic condition characterized by inflammation and deterioration of cartilage. The often painful disease can cause joint deformity and be life-threatening if the respiratory tract, heart valves or blood vessels are affected. The exact mechanism is poorly understood, but it is thought to be related to an immune-mediated attack on particular proteins that are abundant in cartilage.
The diagnosis is reached on the basis of the symptoms and supported by investigations such as blood tests and sometimes other investigations. Treatment may involve symptomatic treatment with painkillers or anti-inflammatory medications, and more severe cases may require suppression of the immune system.
==Signs and symptoms==
Though any cartilage in the body may be affected in persons with relapsing polychondritis, in many cases the disease affects several areas while sparing others. The disease may be variable in its signs and symptoms, resulting in a difficult diagnosis which may leads to delayed recognition for several months, years or decades.〔
Joint symptoms are often one of the first signs of the disease with cartilage inflammation initially absent in nearly half the cases.〔
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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